Availability checked 2026-09-26
The Substance
Have you ever dreamt of a better version of yourself?
HorrorScience Fiction
Where to watch in United States
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Last checked 2026-09-26. Availability changes often.
Availability data: JustWatch via TMDB. How we know this
Overview
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Cast
Demi Moore
Elisabeth
Margaret Qualley
Sue
Dennis Quaid
Harvey
Edward Hamilton-Clark
Fred
Gore Abrams
Oliver
Oscar Lesage
Troy
Christian Erickson
Man at Diner
Robin Greer
Male Nurse
Tom Morton
Doctor
Hugo Diego Garcia
Diego - Boyfriend
Daniel Knight
Casting Director
Jonathon Carley
Assistant Casting Director
Crew
- Director: Coralie Fargeat
- Executive Producer: Erik Baiers
- Executive Producer: Alexandra Loewy
- Executive Producer: Nicolas Royer
- Writer: Coralie Fargeat